Monday, 21 Oct 2019

RA/Inflammatory arthritis

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14 Oct 2019 News Stress and the Risk of Incident Inflammatory Arthritis
13 Oct 2019 Social Study of 179 RA pts achieving remission on TCZ- SC 162 mg qwk randomized to continue qWk or space out to q2Wk -- Weekly Actemra better maintained remission (90% versus 73%; P = 0.004), but then again 73% did well w/ spacing to every other week. https://t.co/ywvsDMxS6M
12 Oct 2019 Social China retrospective study of 727 SoA abd 857 RA pts shows risk of H. Zoster same between SpA & RA (aHZ=0.97), but was significantly higher with MTX (adj HR 3.47) and infliximab (adj HR 10.67) https://t.co/gpictKPpIT
11 Oct 2019 News Juvenile Arthritis at Risk for Coronary Artery Disease
11 Oct 2019 Social FDA grants breakthrough status to OFEV (nintedanib) forthe treatment of chronic fibrosing interstitial lung diseases (ILDs), other than idiopathic pulmonary fibrosis (which it is currently approved for). Nintedanib has been studied in PSS ILD. https://t.co/K0ZTyqrfh6
10 Oct 2019 News Long Delays for Inflammatory Arthritis Patients
09 Oct 2019 Social What do you advise when RA pt complains of growing multiple RA nodules?
08 Oct 2019 Social 225 very early RA in abatacept AVERT study - 44% had high baseline MRI inflammation. With High MRI inflammation, combo ABA+MTX was better than MTX at 12 mos remission by SDAI (45% vs 16%). Pts w/ low baseline MRI inflammation, remission rates did the same https://t.co/A9MRSWaKGB
07 Oct 2019 Social Take the Good with the Bad? Study of 179 RA pts achieving remission on TCZ- SC 162 mg qwk randomized to continue qWk or space out to q2Wk -- Weekly Actemra better maintained remission (90% versus 73%; P = 0.004), but then again 73% did well w/ spacing EOW. https://t.co/Tcb2WwCbc2
07 Oct 2019 Social RT @ACRheum: Arthritis Care & Research Editors Pick: Impact of Patient's Global Assessment on Achieving Remission in Patients With Rheumato…
07 Oct 2019 News Antibiotics Increase Rheumatoid Risk - Again
04 Oct 2019 Social Get the FREE RheumaKnowledgy Card - a pocket guide/aid to the diagnosis, testing and Rx of Rheumatologic, autoimmune and other MSK complaints. https://t.co/oMa3qzh7xt
04 Oct 2019 Social NEJM: Synovial Chondromatosis. A 46-year-old woman with rheumatoid arthritis presented with pain and swelling in both knees. Radiographic findings were consistent with synovial chondromatosis. https://t.co/9jMzE0fuNE
02 Oct 2019 Social MotherToBaby Pregnancy Study in 528 RA pts has shown oral steroid use yields a dose dependent risk of pre-term birth. PTB was increased high dose (RR: 4.77) and medium dose (aRR: 1.81) OCS in the 1st 139 gestational days; DMARDs/biologics were not https://t.co/cuggovK8eL
02 Oct 2019 Social Approximately 20–30% of IBD patients will develop spondyloarthritis. Using a survey tool on 244 IBD pts they found 21% with sufficient criteria to suspect SpA - Other risk factors included being female, Crohn's, prior DMARD or biologic drug use. https://t.co/9Ail7syLmB
01 Oct 2019 Social RT @RheumNow: Survey for Rheumatologists - You would use an MRI in an RA to assess what?
01 Oct 2019 Social Retrospective claims study shows that higher ACPA and RF titers were independently associated with 60-78% increased mortality in established RA; the association persisted in when Rx with DMARDs, but not with biologics. https://t.co/hHJx4alNIQ
01 Oct 2019 Social Study of 101 RA pts w/ baseline Cardiac CT; after median of 83 mos, 48% had progression of plaque; predicted by older age, inflammation & prednisone (p<0.05). Coronary Art. Calcium progressors were older, obese, HTN w/ more inflammation https://t.co/hJRhfja0yk
29 Sep 2019 Social Survey for Rheumatologists - You would use an MRI in an RA to assess what?
29 Sep 2019 Social RT @jeffsparks: 5-factor score for mortality in ANCA-associated vasculitis. I’ve never seen a worse Kaplan-Meier survival curve for those w…