Monday, 16 Dec 2019

Drug Safety

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09 Dec 2019 Social TB is highly endemic in S. Africa - S. African registry reports 97 TB cases in biologic users w/ TB rate 1240/100000 PYs vs zero in biologic naive pts. 1/3 were extra-pulmonary. TB risk highest w/ TNFi Mabs (1683) vs 861 ETN or 681 other MOAs. https://t.co/VUNHVjzkex
08 Dec 2019 Social The RheumNow Podcast is up! Monitoring Methotrexate Safety, Palmoplantar pustulosis, diet in SLE, enthesitis Rx, & benefits of smoking cessation..... Listen here>> https://t.co/zoFp2vc7EB
06 Dec 2019 Social ACR MTX monitoring guidelines from 1994 (Alarcon et al) -pts should be screened for HBV, HCV, Alb. At AST, ALT should be checked at intervals of every 4-8 weeks. MTX should be stopped/adjusted or liver Bx if AST abnl in 5 of 9 (or 6/12) in 12 mos. https://t.co/8lcPz7sH3F
06 Dec 2019 News FDA Warns 15 CBD Manufacturers
05 Dec 2019 News Biologic Safety Guidelines from the British Society for Rheumatology
03 Dec 2019 Social RT @RheumNow: Metanalysis shows that although MTX may blunt some vaccine responses (eg Pneumococcal), the use of MTX, TNF inhibitors and ot…
03 Dec 2019 Blog Pearls Part 2: Common Sense Rheumatology 
03 Dec 2019 Social Norways HUNT study shows NO fracture risk with PPI use in 15,017 women and 13,241 men aged 50–85 years. PPIs were not associated with an increased risk of fracture age-adjusted HR 0.82 (0.67–1.01) for women; 1.05 (0.72–1.52) for men. https://t.co/XIAdvxGTrz
25 Nov 2019 Social The RheumNow Podcast is up! Favorite abstracts from ACR 2019. View it here>> https://t.co/LKCC0y4fCr or listen to the podcast >> https://t.co/bsiY1HI9Dn
25 Nov 2019 Social Pre-existing autoimmune disease is NOT a contraindication to checkpoint inhibitor therapy. 29% flare rate, mostly mild and manageable Abstracts#253 #ACR19 @CCalabreseDO
25 Nov 2019 News Herpes Zoster Vaccine Update
22 Nov 2019 News A Focus on WOCBA (Women of Childbearing Age)
20 Nov 2019 News Influenza Vaccine Updates And Pearls At ACR 2019
20 Nov 2019 ACR Video High Dose Influenza Vaccine Under Age 65: Dr. David Liew
20 Nov 2019 ACR Video Viral Reactivation in Vaccination: Dr. Janet Pope
18 Nov 2019 ACR Video ANCA-Associated Vasculitis Highlights: Dr. David Liew
18 Nov 2019 ACR Video Rituximab-Associated Hypogammaglobulinemia Rates: Dr. Janet Pope and Dr. Stefanie Wade
13 Nov 2019 Social #ACR19 Rheumatology RoundUp - Cushs Abstract Picks: 1223 ALLN-346 Urate Degrading Enzyme L06 Emapalumab in MAS 1890 2357 MTX Safety 1240 anaGO 2292 2279 Biologic WD in Preg 633 631 AS Delays in Dx & referral 196 VTE & ASCVD 2566 Polypharmacy in SLE
13 Nov 2019 Social RT @DrKanikaMonga: Myositis - specific organ involvement joints: MTX, rituximab, abatacept lung: azathioprine, mycophenolate, rituximab ski…
13 Nov 2019 Social RT @Janetbirdope: Do you combine bDMARD with apremilast? #ACR #ACR19 @RheumNow abstract 1481