Friday, 16 Aug 2019

Bone/OP&OA

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13 Aug 2019 News Bisphosphonate Use Associated with Reduced Mortality
13 Aug 2019 Social Osteoarthritis Iniative study of 3053 #OA pts shows worsening in health related quality of life is most rapid with Female gender, higher BMI, smoking, knee pain, and lower income at baseline. Rapid progressors had higher risk of TKR (HR 6.2;CI 3.6–10.7) https://t.co/73OlM7ymH6
12 Aug 2019 Social Nearly 30% of presurgical OA (Spine> Hip &Knee) used prescription opioids. Opioid use was greater w/ spine OA (vs knee), obesity, smokers, depression, greater pain, higher TJC, & concurrent use of other pain meds https://t.co/ns6JBB7BXU
11 Aug 2019 Social Osteoarthritis Iniative study of 3053 #OA pts shows worsening in health related quality of life is most rapid with Female gender, higher BMI, smoking, knee pain, and lower income at baseline. Rapid progressors had higher risk of TKR (HR 6.2;CI 3.6–10.7) https://t.co/73OlM7ymH6
05 Aug 2019 Social The RheumNow Podcast is up – More on osteoporosis, myositis, lipids and gout, testosterone, abatacept in PSS & Boxed Warning for tofacitinib. Watch it here>> https://t.co/I1lBS1lUmY or listen to the Podcast on iTunes or SoundCloud here>> https://t.co/uYyPV7pxcN
04 Aug 2019 Social My advice to Patients on Joint Replacement Surgey: 1) talk to others who had the surgery; 2) consult orthopedics LONG before its urgent; 3) PRE-hab (getting strong before surgery); 4) Get a physical therapist who will work you to normal (3-5X/wk for 4-8 wks)
01 Aug 2019 Social Phase IIb/III trial of multidoses of fasinumab (NGF mAb) in 421 pts w/ mod‐severe hip or knee #OA (WOMAC pain ~6+) showed signif reductions in pain (LMS -1.1 to -1.4) vs PBO (-.79) & >30% improved pain by @wk16 (63–74 vs 47%); arthropathy 7% FAS vs 1%PBO https://t.co/UtkqDE5lGf
30 Jul 2019 Social Is tea consumption associated with a risk of fractures? A metanalysis of 16 studies, 772,707 participants, high (compared to low) tea consumption was associated a lower fracture risk - RR 0.86 (0.78–0.94). https://t.co/24XYyUArS9
22 Jul 2019 News Partial or Total Knee Replacement for Osteoarthritis?
18 Jul 2019 News Intraarticular Capsaicin in Knee Osteoarthritis
18 Jul 2019 News Increased Risk of Cardiovascular Death in Hip and Knee Osteoarthritis
16 Jul 2019 Social Analysis #osteoarthritis clinical trials placebo response ratio (PRR) as the placebo to treatment effect size ratio. PRR was best for walking time/distance (0.30, 95% CI 0.16 to 0.43) and worst for PRO pain (0.44, 95% CI 0.23 to 0.65) https://t.co/4VorQdSIV2
10 Jul 2019 News Safety Concerns Offset the Modest Improvements of Tanezumab in Osteoarthritis
08 Jul 2019 News Benefits vs Harms for Osteoporosis Drug Continuation or Discontinuation
27 Jun 2019 News Mortality from Falls in the Elderly
25 Jun 2019 Social 2,899 RA and 112,571 OA pts had THA or TKA. RA had more infections (HR 1.29;1.03-1.61) post THA/TKA, but fewer VTE (HR 0.60; 0.26-0.98) post TKA. Biologics in RA had a similar infx risk but more VTE (HR 4.82;1.67-13.9) vs non-biologics. https://t.co/Lv1QLbjZjx
24 Jun 2019 Social After reviewing the safety data, the FDA has removed the risk ofosteoporosis and fracture from the drug facts listing for OTC proton pump inhibitor (PPI) medications https://t.co/RnjtTl2oVV
18 Jun 2019 Social RT @GoutGroup: Achilles’ tendon issues can be painful and disabling, and are something we all want to avoid. Dr Simon Otter presents imagin…
17 Jun 2019 Social RT @sclerodermaUM: Going beyond scleroderma. 1. Tanezumab is effective for OA related pain and no new safety concerns. #EULAR2019 https://…
04 Jun 2019 News Knee Injuries Increases Osteoarthritis Risk